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643 Grand AVE, South San Francisco
$998,888
3 Beds ⋅ 4 Baths ⋅ ML82059314 MLS
Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging and an additional 2 car off street parking in front of the house. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

643 Grand AVE, South San Francisco

Listing courtesy of Jill Penna, 415-244-8630 from Christie's International Real Estate Sereno
(If provided) CoList: from

1 Mandalay PL 1510, South San Francisco
$924,800
2 Beds ⋅ 2 Baths ⋅ ML82059246 MLS
Set against the scenic backdrop of San Bruno Mountain Ecological Reserve, well-maintained 2 BD, 2 BA corner penthouse offers 1,440 sqft of modern high-rise elegance w/ soaring ceilings. The grand lobby ft. a dazzling chandelier and sunlit lounge. Inside, open living & dining area is flooded w natural light, framed by sweeping mountain views through oversized windows. Hardwood floors run throughout, while plush carpet in the bedrooms adds warmth. The chef-inspired kitchen ft designer cabinetry, granite counters, and stainless steel appliances. The primary suite includes a walk-in closet with custom organization and a spacious bathroom. The second bedroom offers a comfortable, private feel, and an in-unit washer & dryer adds convenience. Additional perks: 2 dedicated parking spaces, guest parking, and access to fitness center, business center, clubroom, and landscaped patio. Key fob entry and a package room add security. As a corner unit, the home benefits from added natural light and extra windows. Location is unbeatable, minutes from Highway 101, with Costco, Oyster Point dining, and Marina Park's waterfront paths nearby. The San Bruno Mountain Ridge Trail begins right outside your door elevated comfort, timeless style, and one of the best lifestyles the Bay Area has to offer.

1 Mandalay PL 1510, South San Francisco

Listing courtesy of OWN Real Estate, 650-888-0153 from KW Advisors
(If provided) CoList: from

22 Sonora AVE, South San Francisco
$919,900
3 Beds ⋅ 1 Baths ⋅ ML82059151 MLS
Opportunity awaits at 22 Sonora Avenue! This 3-bedroom, 1-bath home offers an efficient two-level floor plan and plenty of potential for its next owner. The main level features a light-filled living room with multiple windows, an eat-in kitchen, and one bedroom. Upstairs, you'll find two additional bedrooms connected by an open landing area beneath charming pitched ceilings. An attached one-car garage and generous backyard provide added space and possibilities. Owned by the same family for many years, the home is ready for its next chapter and an opportunity for a buyer to renovate and make it their own. Convenient South San Francisco location near shopping, transportation, and everyday amenities. Bring your vision and imagine the possibilities!

22 Sonora AVE, South San Francisco

Listing courtesy of Jennifer Doak, 408-799-3737 from Intero Real Estate Services
(If provided) CoList: from

7222 Shannon Park CT, South San Francisco
$1,798,000
4 Beds ⋅ 4 Baths ⋅ ML82058691 MLS
Nestled in the highly coveted Westborough Hills of South San Francisco, welcome to this spacious and inviting 4-bedroom, 3.5-bath well crafted home for comfortable living and entertainment in a three-level setting. Featuring generous living spaces with very high ceilings, well-appointed bedrooms, and modern remodeled bathrooms, this home offers the perfect blend of style, functionality, and convenience. The open and welcoming layout provides plenty of room for everyday living, while the four bedrooms offer flexibility for family, guests, or home office, with easy accessibility to a ground level bedroom and full bath. Top floor offers sweeping panoramic views where you can enjoy breathtaking sunrises every morning over the city skyline. The home offers a large back deck and a private estate entrance and security. Don't miss an opportunity to own property in the booming Biotech capital of California, just 10 minutes away midst the best part of the city and 10 minutes from scenic Highway 1 and ocean beaches. Regular sale with a clean and clear title history for an easy close of escrow.

7222 Shannon Park CT, South San Francisco

Listing courtesy of Ravi Sen, 650-444-6623 from Maxim Solution Realty Corporation
(If provided) CoList: from

1400 El Camino Real 220, South San Francisco
$929,888
2 Beds ⋅ 2 Baths ⋅ ML82059098 MLS ⋅ Camino Court Complex BLDG.
Elevate your lifestyle at 1400 El Camino Real #220, a sleek and sunlit S. San Francisco sanctuary 2bed, 2 Full Baths, with a LOFT. Flex-Space, 2 Car Parking Covered & Gated (A3 & A4 spots) elevator access, go rent extra parking. Delivering an effortless blend of modern comfort and low-maintenance style, the bright, open-concept layout flows seamlessly to accommodate your remote work setup, quiet relaxation, or weekend entertaining. LOCATION, LOCATION and LOCATION is noteworthy as it is in Close Proximity to the SSF BART, COSTCO Warehouse Store; Pacific Super Grocery; Trader Joes; Grocery Outlet: StarBucks and KAISER Hospital. Not to forget to mention its proximity to banks such as B of A, Citi and Wells Fargo lcated at the Chestnut shopping area. With fast access to Hwy 101 and 280 for seamless San Francisco or Silicon Valley trips, this home is the ultimate match for first-time buyers or savvy investors looking for location, light, and connected urban living. Bring your design vision, drop your bags, and start living your best South City chapter! Seller may consider a credit toward an eligible buyers temporary mortgage-payment buydown, subject to offer terms, loan-program limits and lender approval. Buyers should consult preferred lender. Watch video to appreciate the home.

1400 El Camino Real 220, South San Francisco

Listing courtesy of Dino Banzon, 650-745-6384 from BANZON REALTY
(If provided) CoList: from

335 A ST, South San Francisco
$1,150,000
3 Beds ⋅ ML82058845 MLS
Rare opportunity to buy this wonderful duplex in South San Francisco's desirable Orange Park neighborhood. The upper unit (#335) offers approximately 1171 sf with two bedrooms, two full baths (primary remodeled in 2010), kitchen (remodeled in 2004), dining room, living room, enclosed sunroom with views, and decks. Owners did an addition in 1998 with permits. This unit is currently owner occupied. The lower unit (#337) is fully electric and offers approximately 998 sf with one bedroom and one full bath. There's also a bonus room that can be utilized as a bedroom or office and a deck with access to the backyard. The kitchen and bathroom were remodeled in 2000 and the owners did an addition in 2000 with permits. This unit is currently vacant. Double pane windows throughout, newer roof (7 years), views from #335, shared yard with storage shed and washer/dryer is included. Plenty of storage, ample parking, Prime location near downtown shops, restaurants, schools, transportation, major biotech hub.

335 A ST, South San Francisco

Listing courtesy of Richard Michaels, 650-888-9963 from Heritage Realty
(If provided) CoList: from

157 A ST, South San Francisco
$889,000
2 Beds ⋅ 1 Baths ⋅ ML82058178 MLS
Welcome to 157 A Street, a charming South San Francisco home where classic character meets thoughtful updates. Beautifully refreshed with new interior and exterior paint and updated fixtures throughout, this inviting residence is polished, welcoming, and ready to enjoy from day one. Inside, natural light and original character create a warm sense of home. Beautiful parquet hardwood floors bring richness and charm to the living spaces, while the corner fireplace creates an inviting focal point and a cozy place to gather. The sunny eat in kitchen offers a cheerful setting for morning coffee, casual meals, and everyday living, while two comfortable bedrooms and a well-appointed bath complete the home's thoughtfully designed interior. Outside, a private yard offers a lovely extension of the living space, with room to relax, garden, or entertain. An attached garage with laundry hookups adds everyday convenience. Ideally situated near downtown South San Francisco, with easy access to shopping, dining, BART, Caltrain, SFO, and major commuter routes, 157 A Street offers an appealing combination of character, convenience, and move in ready comfort in the heart of the Peninsula.

157 A ST, South San Francisco

Listing courtesy of Travis Conte, 650-520-5753 from Berkshire Hathaway HomeServices Drysdale Propertie
(If provided) CoList: from

811 Marcie CIR, South San Francisco
$498,000
1 Beds ⋅ 1 Baths ⋅ ML82053892 MLS ⋅ Willow Grand HOA BLDG.
Why rent when you can own? Welcome to 811 Marcie Circle, South San Francisco spacious and well-maintained 1-bedroom, 1-bathroom lower-level home offering comfort, convenience, and exceptional value. The generous floor plan features a bright living area that opens to a private patio, creating the perfect space to enjoy your morning coffee, unwind after a long day, or entertain friends. The home also offers secure garage parking with one dedicated parking space and private lockable storage, providing added convenience and peace of mind. A shared washer and dryer are conveniently located in the garage just steps from your front door. With just a few steps down to the front door, everyday living is easy, making it convenient to carry groceries, luggage, and packages into your home. Ideally located near shopping, dining, parks, BART, Caltrain, major freeways, and South San Francisco's thriving biotech hub, commuting and everyday errands are a breeze. Whether you're a first-time homebuyer, downsizing, or looking for a great investment opportunity, this is your chance to stop renting and start building equity. Don't miss this wonderful opportunity to own a home in one of the Peninsula's most convenient locations!

811 Marcie CIR, South San Francisco

Listing courtesy of Rachel Ni, 650-455-1500 from Coldwell Banker Realty
(If provided) CoList: from

128 Gardiner AVE, South San Francisco
$1,298,000
4 Beds ⋅ ML82055089 MLS
**Prime Duplex Opportunity in South San Francisco** Discover this exceptional duplex in one of S. San Francisco's most sought-after neighborhoods. This well-maintained property features two spacious units, each offering 2 bedrooms and 1 bathroom. An outstanding opportunity for investors or future owner-occupants, this property offers excellent income potential and long-term appreciation in a prime Peninsula location. Both units are currently tenant-occupied, providing immediate rental income. ** Conveniently located near vibrant Grand Avenue, shopping, restaurants, the Costco Business Center, major biotech employers, Highway 101, and Gardiner Park, Don't miss out on this exceptional opportunity!

128 Gardiner AVE, South San Francisco

Listing courtesy of Loletta Wong, 415-218-1146 from Intero Real Estate Services
(If provided) CoList: from

338 N Canal Street Unit 20, South San Francisco
$1,490,000
426142142 MLS
Thoughtfully designed and renovated for efficiency, this warehouse office seamlessly blends functionality with modern comfort. The interior features a well-appointed kitchenette, two restrooms, and an Aquasana whole-house water filtration system complete with a salt-free water conditioner, whole-house filter, sediment pre-filter, and UV purifier ensuring premium water quality throughout. Generous storage space adds to the unit's practicality. Operationally, this warehouse excels with dual access points, including a dedicated loading dock door and a separate front office entrance, streamlining daily business operations. Additional highlights include 3 designated parking spaces and an impressive 14+ foot roll-up door, ideal for a wide range of industrial uses.

338 N Canal Street Unit 20, South San Francisco

Listing courtesy of Victoria C Lam, from Coldwell Banker Realty
(If provided) CoList: from

889 McLellan DR 210, South San Francisco
$1,385,000
3 Beds ⋅ 2 Baths ⋅ ML82052287 MLS ⋅ Sterling Place BLDG.
RARE NEW CONSTRUCTION! Discover modern luxury living in a brand-new condominium community ideally located across the road from the South San Francisco BART Station and next to Trader Joes. One-, two-, and three-bedroom floor plans are available, offering flexibility for a variety of lifestyles. Enjoy exceptional convenience with shopping, schools, hospitals, and public transportation nearby, while still coming home to a peaceful and quiet environment. The BART goes underground nearby, and triple-pane windows help block outside noise for added comfort. Each residence features high ceilings, large floor-to-ceiling windows, and bright open living spaces. Homes are thoughtfully finished with Samsung appliances, Daikin air conditioning, Hansgrohe faucets, Toto toilets, and owned solar panels for energy savings and everyday efficiency. Experience the perfect blend of luxury, convenience, and sustainability in South San Francisco. One-, Two- and three-bedroom model homes are available.

889 McLellan DR 210, South San Francisco

Listing courtesy of Lisa Feng, 650-554-0050 from Peter Suen, Broker
(If provided) CoList: from

889 McLellan DR 206, South San Francisco
$919,000
2 Beds ⋅ 2 Baths ⋅ ML82051562 MLS ⋅ Sterling Place BLDG.
RARE NEW CONSTRUCTION! Discover modern luxury living in a brand-new condominium community ideally located across the road from the South San Francisco BART Station and next to Trader Joes. One-, two-, and three-bedroom floor plans are available, offering flexibility for a variety of lifestyles. Enjoy exceptional convenience with shopping, schools, hospitals, and public transportation nearby, while still coming home to a peaceful and quiet environment. The BART goes underground nearby, and triple-pane windows help block outside noise for added comfort. Each residence features high ceilings, large floor-to-ceiling windows, and bright open living spaces. Homes are thoughtfully finished with Samsung appliances, Daikin air conditioning, Hansgrohe faucets, Toto toilets, and owned solar panels for energy savings and everyday efficiency. Experience the perfect blend of luxury, convenience, and sustainability in South San Francisco. One-, Two- and three-bedroom model homes are available.

889 McLellan DR 206, South San Francisco

Listing courtesy of Lisa Feng, 650-554-0050 from Peter Suen, Broker
(If provided) CoList: from

200 Linden Avenue Unit 410, South San Francisco
$999,000
2 Beds ⋅ 2 Baths ⋅ 426138034 MLS
NOW OFFERED AT $999,000! Discover Residence 410 at The Linden, a spacious 2-bedroom, 2-bath condominium with a versatile den in the heart of Downtown South San Francisco. Built in 2021 and offering approximately 1,230 sq. ft., this modern home features an open-concept layout, abundant natural light, and flexible living space ideal for today's lifestyle. The primary suite includes dual walk-in closets, while the separate den provides the perfect space for a home office, playroom, or additional living area. One of Residence 410's most distinctive features is its convenient access to the beautifully landscaped resident courtyardan inviting extension of the home's living space for relaxing or gathering outdoors. Additional highlights include in-unit laundry, deeded garage parking, bike storage, secure building access, and convenient elevator access. Residents of The Linden also enjoy a rooftop terrace, resident lounge and gathering spaces, and a modern lobby with secure mailroom. Ideally situated near Downtown SSF's restaurants, shopping, Caltrain, BART, SFO, and major commuter routes. Modern construction, generous square footage, flexible space, and a prime Peninsula locationall under $1M.

200 Linden Avenue Unit 410, South San Francisco

Listing courtesy of Sofia L Bayawa, from All Season Realty & Mortgage Services
(If provided) CoList: from

889 McLellan DR 205, South San Francisco
$799,000
1 Beds ⋅ 1 Baths ⋅ ML82046471 MLS ⋅ Sterling Place BLDG.
RARE NEW CONSTRUCTION! Discover modern luxury living in a brand-new condominium community ideally located across the road from the South San Francisco BART Station and next to Trader Joes. One-, two-, and three-bedroom floor plans are available, offering flexibility for a variety of lifestyles. Enjoy exceptional convenience with shopping, schools, hospitals, and public transportation nearby, while still coming home to a peaceful and quiet environment. The BART goes underground nearby, and triple-pane windows help block outside noise for added comfort. Each residence features high ceilings, large floor-to-ceiling windows, and bright open living spaces. Homes are thoughtfully finished with Samsung appliances, Daikin air conditioning, Hansgrohe faucets, Toto toilets, and owned solar panels for energy savings and everyday efficiency. Experience the perfect blend of luxury, convenience, and sustainability in South San Francisco. Two- and three-bedroom model homes are available.

889 McLellan DR 205, South San Francisco

Listing courtesy of Lisa Feng, 650-554-0050 from Peter Suen, Broker
(If provided) CoList: from

20 Maple AVE, South San Francisco
$885,000
2 Beds ⋅ 1 Baths ⋅ ML82045331 MLS
Welcome to 20 Maple Ave, a beautifully maintained Craftsman cottage blending early 20th-century character with modern updates. Situated on a desirable corner lot in "Old South SF," this two-bedroom home offers a warm atmosphere just steps from downtown. Step through the formal entry into a living room anchored by a stone fireplace. The home features hardwood floors, fresh paint, and updated lighting. The modern eat-in kitchen boasts quartz countertops, a farmhouse sink, and stainless appliances, while maintaining original charm. A dedicated mudroom and laundry area provide a practical transition to the outdoors. Enjoy a private retreat in the fenced backyard and patio, ideal for relaxing. The property includes a detached garage for secure parking. Located minutes from Grand Avenue, biotech hubs, and Caltrain, this home is a commuters dream. 20 Maple Ave is a rare find ,capturing the essence of California cottage living.

20 Maple AVE, South San Francisco

Listing courtesy of OWN Real Estate, 650-888-0153 from KW Advisors
(If provided) CoList: from

560 Eccles AVE, South San Francisco
$41,000,000
ML82044309 MLS ⋅ USDA - United States Department BLDG.
PHENOMENAL INVESTMENT | SECURED 13-YEAR FEDERAL GOVERNMENT TENANT | TRIPLE NET | BUILT IN 2019 | SOUTH SF BIOTECH HUB! A rare investment opportunity in the heart of South San Francisco's world-renowned biotech and life sciences hub! Purpose-built in 2019, this premier 21,552 SF high-tech facility sits on an expansive 3.65-acre site and offers the stability of a secured 13-year federal government tenant under a Triple Net lease, combined with sophisticated, mission-critical infrastructure. The facility features approximately 9,500 SF of professional office space, 4,500 SF of specialized laboratory space, and a 7,000 SF warehouse and inspection area. The technical build-out includes multiple entomology and botany labs, 100% ducted exhaust, high-purity reverse osmosis water systems, a 500kW stand-alone diesel generator, and dedicated UPS backup power. Designed for secure government operations, the property features a Lenel card-access system, 24-hour CCTV, blast-mitigation windows, secured fencing, four interior dock-high doors accommodating 53-foot tractor-trailers, and 62 assigned parking spaces. Strategically positioned within the South San Francisco Life Science cluster. Don't miss this phenomenal opportunity!

560 Eccles AVE, South San Francisco

Listing courtesy of John Tran, 408-931-0897 from KW Elevate
(If provided) CoList: Avi Luzon from Keller Williams Thrive

2637 Bantry CT, South San Francisco
$1,198,000
3 Beds ⋅ 4 Baths ⋅ ML82043394 MLS ⋅ Bayview 22 at Oakmont Owners BLDG.
Tucked away in the heart of South San Francisco, this beautifully updated single-family home offers the perfect blend of modern style, comfort, and convenience. Step inside to a light-filled interior featuring refined finishes and an inviting floor plan designed for both everyday living and effortless entertaining. The updated kitchen boasts sleek countertops, contemporary cabinetry, and quality appliances, making it as functional as it is stylish. Spacious bedrooms provide a peaceful retreat, while the tastefully remodeled bathrooms showcase elevated finishes and a spa-inspired feel. Thoughtfully updated throughout, this home combines timeless design with everyday comfort in a highly desirable location.

2637 Bantry CT, South San Francisco

Listing courtesy of Travis Conte, 650-520-5753 from Berkshire Hathaway HomeServices Drysdale Propertie
(If provided) CoList: from

451 Victory AVE 5, South San Francisco
$499,000
ML82035557 MLS ⋅ Victory Business Center BLDG.
Units 4 and 5 are currently combined via two interior openings: one located within the groundfloor front office area and a second opening on the second floor, also within the office area. Unit 5 features a reception area, a ground-floor office, and a connecting hallway linking Units 4 and 5. The warehouse area includes two ADA-compliant restrooms, a stairwell providing access to the second-floor offices, and a separate staircase leading to the storage mezzanine. The second floor offers four offices, including two located toward the rear above the warehouse-- one with direct access to the mezzanine--and two front-facing offices with windows overlooking the parking lot. An additional hallway on the second floor also connects Units 4 and 5. Wall Opening to Unit 4. Commercial Owners' Association (COA) is $817 a month.

451 Victory AVE 5, South San Francisco

Listing courtesy of Stanley Lo, 650-373-0007 from Green Banker Realty
(If provided) CoList: from

451 Victory AVE 4, South San Francisco
$499,000
ML82035565 MLS ⋅ Victory Business Center BLDG.
Units 4 and 5 are currently combined via two interior openings: one located within the groundfloor front office area and a second opening on the second floor, also within the office area. Unit 4 features two ground-floor offices and a connecting hallway linking Units 4 and 5. A rear service room between the office area and warehouse contains two ADA-compliant restrooms and a stairwell providing access to the second floor. The second floor includes a conference room situated above the warehouse, followed by a work area equipped with a garage door opening over the warehouse for convenient forklift access. Two additional offices are located at the front of the second floor, along with another hallway connecting Units 4 and 5. Commercial Owners' Association (COA) is $817 a month.

451 Victory AVE 4, South San Francisco

Listing courtesy of Stanley Lo, 650-373-0007 from Green Banker Realty
(If provided) CoList: from

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